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embryonic stem cells e14 tg2a male atcc crl 1821  (ATCC)


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    ATCC embryonic stem cells e14 tg2a male atcc crl 1821
    Embryonic Stem Cells E14 Tg2a Male Atcc Crl 1821, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 485 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/embryonic+stem+cells/ES-E14TG2a/pm42242215-230-57-63
    Average 96 stars, based on 485 article reviews
    embryonic stem cells e14 tg2a male atcc crl 1821 - by Bioz Stars, 2026-10
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    Cell Culture:

    Article Title: Morphological observation of embryoid bodies completes the in vitro evaluation of nanomaterial embryotoxicity in the embryonic stem cell test (EST).
    Article Snippet: 28 29 30 31 32 33 34 35 36 37 38 39 Article history: Received 29 January 2015 Revised 25 May 2015 Accepted 16 June 2015 Available online xxxx

    Article Title: Neural crest related gene transcript regulation by valproic acid analogues in the cardiac embryonic stem cell test.
    Article Snippet: In vivo, neural crest (NC) cells contribute critically to heart formation.. The embryonic stem cells in the cardiac Embryonic Stem cell Test (ESTc) differentiate into a heterogeneous cell population including non-cardiomyocyte cells.. The use of molecular biomarkers from different mechanistic pathways can refine quantitative embryotoxicity assessment.

    Incubation:

    Article Title: Morphological observation of embryoid bodies completes the in vitro evaluation of nanomaterial embryotoxicity in the embryonic stem cell test (EST).
    Article Snippet: 28 29 30 31 32 33 34 35 36 37 38 39 Article history: Received 29 January 2015 Revised 25 May 2015 Accepted 16 June 2015 Available online xxxx

    Expressing:

    Article Title: Method for controlling differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating SIRT1 expression
    Article Snippet: .. Preparation and Culture of Mouse Embryonic Stem Cells In the present disclosure, R1 cells which are embryonic stem cells were purchased from American Type Culture Collection (ATCC; ATCC SCRC-1011) and used, In order to determine whether a differentiation of embryonic stem cells into adipocytes was affected by the presence or absence of SIRT1 protein expression, the control which is embryonic stem cells (SIRT1+/+; WT) expressing the SIRT1 gene and mouse embryonic stem cells lacking SIRT1 genes (SIRT1−/−; KO) were prepared (Han M K et al., Cell Stem Cell., March 6; 2 (3): 241, 2008). .. The mouse embryonic stem cells were cultured in Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 2 mM GlutaMAXTM (Gibco, USA), 1× Non-essential amino acid (1×NEAA; Gibco, USA), 0.1 mM beta-mercaptoethanol (B-mercaptoethanol; Invitrogen, USA) and 103 unit/ml leukemia inhibitory factor (LIF; Milipore, USA).

    Article Title: Reprogramming a cell by inducing a pluripotent gene through RNA interference
    Article Snippet: .. Expression levels will be compared to those in untreated control cells and federally-approved human embryonic stem cells (ATCC) relative to cyclophilin. ..

    Control:

    Article Title: Method for controlling differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating SIRT1 expression
    Article Snippet: .. Preparation and Culture of Mouse Embryonic Stem Cells In the present disclosure, R1 cells which are embryonic stem cells were purchased from American Type Culture Collection (ATCC; ATCC SCRC-1011) and used, In order to determine whether a differentiation of embryonic stem cells into adipocytes was affected by the presence or absence of SIRT1 protein expression, the control which is embryonic stem cells (SIRT1+/+; WT) expressing the SIRT1 gene and mouse embryonic stem cells lacking SIRT1 genes (SIRT1−/−; KO) were prepared (Han M K et al., Cell Stem Cell., March 6; 2 (3): 241, 2008). .. The mouse embryonic stem cells were cultured in Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 2 mM GlutaMAXTM (Gibco, USA), 1× Non-essential amino acid (1×NEAA; Gibco, USA), 0.1 mM beta-mercaptoethanol (B-mercaptoethanol; Invitrogen, USA) and 103 unit/ml leukemia inhibitory factor (LIF; Milipore, USA).

    Article Title: Reprogramming a cell by inducing a pluripotent gene through RNA interference
    Article Snippet: .. Expression levels will be compared to those in untreated control cells and federally-approved human embryonic stem cells (ATCC) relative to cyclophilin. ..

    Modification:

    Article Title: Ascorbic acid delivered by mesoporous silica nanoparticles induces the differentiation of human embryonic stem cells into cardiomyocytes.
    Article Snippet: Contents lists available at ScienceDirect Materials Science and Engineering C j ourna l homepage: www.e lsev ie r .com/ locate /msec Ascorbic acid delivered by mesoporous silica nanoparticles induces the differentiation of human embryonic stem cells into cardiomyocytes Mingming Ren ⁎, Zhen Han, Jinglai Li, Gang Feng, Shuyuan Ouyang Cardiovascular Surgery, Peking University Shenzhen Hospital, Shenzhen, China ⁎ Corresponding author.. E-mail address: mmren123@163.com (M. Ren). http://dx.doi.org/10.1016/j.msec.2015.06.048 0928-4931/© 2015 Elsevier B.V. All rights reserved. a b s t r a c t a r t i c l e i n f o Article history: Received 7 April 2015 Received in revised form 1 June 2015 Accepted 25 June 2015 Available online 2 July 2015 Keywords: Human embryonic stem cells Ascorbic acid Differentiation Cardiomyocytes Mesoporous silica nanoparticles Embryonic stem (ES) cells offer the potential to generate all cell types in the body, which provide a promising approach to repair tissue damage or dysfunction.. In the past decade, great efforts have beenmade to induce the differentiation of ES cells into numerous types of cells, such as adipocytes, neurocytes and cardiomyocytes.



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    embryonic stem cells e14 tg2a male atcc crl 1821  (ATCC)
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A <t>H9</t> hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A <t>H9</t> hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A <t>H9</t> hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A <t>H9</t> hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A <t>H9</t> hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.
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    Pluripotency and differentiating capacity <t>of</t> <t>embryonic</t> stem cells <t>(ESCs).</t> ESCs are created from the inner cell mass (ICM) of the blastocyst stage. They can develop into all three germ layers: the ectoderm (which later gives rise to the brain, skin, and eyes), the endoderm (which gives rise to the lungs, liver, and gut), and the mesoderm (which gives rise to the bones, blood, and muscles). ESCs undergo in vitro differentiation using specific protocols, forming embryoid bodies that mimic early-stage embryogenesis. They may also be implanted in vivo, where they can assist in tissue regeneration. Still, they may, in rare cases, develop into teratomas: complex tumors that contain tissues from all three germ layers. ESCs may also assist in repairing organs, although they may be unregulated and pose risks such as teratocarcinoma.
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    embryonic stem cell line wa09  (WiCell Research Institute Inc)
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    Pluripotency and differentiating capacity <t>of</t> <t>embryonic</t> stem cells <t>(ESCs).</t> ESCs are created from the inner cell mass (ICM) of the blastocyst stage. They can develop into all three germ layers: the ectoderm (which later gives rise to the brain, skin, and eyes), the endoderm (which gives rise to the lungs, liver, and gut), and the mesoderm (which gives rise to the bones, blood, and muscles). ESCs undergo in vitro differentiation using specific protocols, forming embryoid bodies that mimic early-stage embryogenesis. They may also be implanted in vivo, where they can assist in tissue regeneration. Still, they may, in rare cases, develop into teratomas: complex tumors that contain tissues from all three germ layers. ESCs may also assist in repairing organs, although they may be unregulated and pose risks such as teratocarcinoma.
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    (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A H9 hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.

    Journal: bioRxiv

    Article Title: Deep Learning-Guided Holotomography Reveals Early Structural Remodelling During Pluripotency Exit

    doi: 10.64898/2026.04.23.720508

    Figure Lengend Snippet: (a) Transcriptomic analysis of the time-course differentiation process. Loss of pluripotency markers is visible over time. (b) A GM25256 hiPSC colony after 12 h of RA-induced differentiation. The red arrow indicates filopodium-like membrane protrusion at colony periphery. The green arrow indicates an intercellular gap. (c) A GM25256 hiPSC colony after 24 h of RA-induced differentiation. (d) A GM25256 hiPSC colony after 48 h of RA-induced differentiation. The red arrow indicates a jagged colony boundary. ( e ) A GM25256 hiPSC colony after 96 h of RA-induced differentiation. The red arrow indicates an intercellular gap near the colony periphery. ( f ) A H9 hESC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (g) Ratio of H9 hESC colonies with average P undiff over 0.5. (h) A KOLF2.1J hiPSC colony both untreated and after 24 h of RA-induced differentiation. P undiff was measured by DeepHOPE. (i) Ratio of KOLF2.1J hiPSC colonies with average P undiff over 0.5. Scale bar (B to H) = 50 μm.

    Article Snippet: The human embryonic stem cell line H9 (WA09, WiCell) and human iPSCs lines GM25256 (Coriell Institute) and KOLF2.1J (The Jackson Laboratory) were used to generate the base model for this study.

    Techniques: Membrane

    Pluripotency and differentiating capacity of embryonic stem cells (ESCs). ESCs are created from the inner cell mass (ICM) of the blastocyst stage. They can develop into all three germ layers: the ectoderm (which later gives rise to the brain, skin, and eyes), the endoderm (which gives rise to the lungs, liver, and gut), and the mesoderm (which gives rise to the bones, blood, and muscles). ESCs undergo in vitro differentiation using specific protocols, forming embryoid bodies that mimic early-stage embryogenesis. They may also be implanted in vivo, where they can assist in tissue regeneration. Still, they may, in rare cases, develop into teratomas: complex tumors that contain tissues from all three germ layers. ESCs may also assist in repairing organs, although they may be unregulated and pose risks such as teratocarcinoma.

    Journal: Regenerative Therapy

    Article Title: Engineering cardiac regeneration using stem cells: Cellular sources, differentiation signatures, targeted delivery, and functional recovery

    doi: 10.1016/j.reth.2026.101120

    Figure Lengend Snippet: Pluripotency and differentiating capacity of embryonic stem cells (ESCs). ESCs are created from the inner cell mass (ICM) of the blastocyst stage. They can develop into all three germ layers: the ectoderm (which later gives rise to the brain, skin, and eyes), the endoderm (which gives rise to the lungs, liver, and gut), and the mesoderm (which gives rise to the bones, blood, and muscles). ESCs undergo in vitro differentiation using specific protocols, forming embryoid bodies that mimic early-stage embryogenesis. They may also be implanted in vivo, where they can assist in tissue regeneration. Still, they may, in rare cases, develop into teratomas: complex tumors that contain tissues from all three germ layers. ESCs may also assist in repairing organs, although they may be unregulated and pose risks such as teratocarcinoma.

    Article Snippet: Embryonic Stem Cells (ESCs) , - Regeneration of damaged myocardium - replacement of cardiomyocytes , Differentiation into functional cardiomyocytes , Geron Corporation studies (preclinical models) [ ] .

    Techniques: Muscles, In Vitro, In Vivo